NOT KNOWN FACTUAL STATEMENTS ABOUT PKRRATING

The activated enzyme then phosphorylates its significant substrate, the translational initiation element eIF2α. The ensuing translational arrest blocks viral replication. PKR belongs into a conserved family members of 4 protein kinases (PKR, PERK, GCN2, HRI) that all phosphorylate eIF2α in response to distinctive stimuli12, triggering the built-i